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Dr Jamie Walker

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Dr Jamie Walker

Senior Lecturer

Location: Laver Building 906

Telephone: 01392 723933

Extension: (Streatham) 3933

I am an MRC Research Fellow with interests in complex dynamical processes in neuroscience and neuroendocrinology. Using a multidisciplinary approach, combining predictive mathematical modelling and analysis with experimental biology, I am currently focused on understanding how the hypothalamic-pituitary-adrenal (HPA) axis regulates the pulsatile secretion of vital glucocorticoid hormones, and why the dynamics of this system changes in different physiological and pathological conditions. This is an important question to address because pulsatile patterns of glucocorticoids are important for the dynamic regulation of gene expression, as well as for more rapid non-genomic effects of glucocorticoids on neuronal function (e.g. synaptic transmission) and behavioural activity (e.g. stress responsiveness and aggression).