Natural Sciences

Biology, Chemistry and Physics are the core Disciplines upon which our scientific understanding and teaching are based. Physics underpins our understanding of the real world with a mathematical framework based on fundamental laws; Chemistry derives knowledge of the composition, properties and behaviour of matter and materials; while Biology investigates the living world, deriving general principles and obtaining detailed insight into the way in which units of life relate to one another. In this module, you will be introduced to the key concepts of each Discipline, while recognising the inter-reliance of each in understanding the Natural World.

This is a compulsory module for students on the BSc/MSci Natural Sciences and should be taken in parallel with NSC1001 Frontiers in Science 1 and NSC1002 Mathematics and Computer Science: Integrative Tools for Natural Sciences.

The module aims to provide you with a detailed understanding of the core concepts surrounding Biology, Chemistry and Physics. The intention is that you will complete the module with a breadth of understanding sufficient to allow you to undertake core second year modules in each Discipline. Specifically:

Biology: You will be introduced to the concepts of the biological diversity, evolution, the genetic basis of life and the boundaries that encompass biological systems. You will then explore the fundamental principles underlying these systems, at the level of the biochemical reaction, the cell, the tissue, the entity, the population and the environment. Specific examples will be used to reinforce your understanding and to relate the chemical and physical principles taught in the other areas of the module, to the biological world.

Chemistry: We will teach you how energy quantisation leads to the atomic and molecular orbitals that govern the physicochemical properties of substances and how to apply this knowledge in rationalising chemical reactivity and bonding. We will show you how to apply the laws of thermodynamics to predict the position of chemical equilibrium and how theories of reaction kinetics are used to interpret experimental data for reaction rates. We will teach you the nomenclature, structural representations and reaction mechanisms of organic chemistry, showing you how to apply this knowledge in chemical synthesis.

Physics: We will teach you how to make quantitative predictions about the physical world by combining physical principles to build mathematical models. You will be introduced to fundamental physical principles and some standard models of physics, including models for atoms, solids, liquids and gases, and light and sound. You will be guided in how to apply the principles of physics in new situations and manipulate mathematical formulae to build quantitative physical models. Your problem-solving strategies and strategies for identifying and remedying missing knowledge will be developed.

On successful completion of this module you should be able to:

Module Specific Skills and Knowledge

Discipline Specific Skills and Knowledge

Personal and Key Transferable / Employment Skills and Knowledge

Biological Content Summary

We will begin by addressing the concepts of space (boundaries), time, quantities and relationships of entities within the Biological world before concentrating on the key roles of genetic variation and the environment in evolution and the generation of diversity. We will then teach you the fundamental principles that underlie complexity on biology, leading you through two distinct streams: in one, we will build up your understanding from the perspective of the gene; how it relates to protein, and how protein structure relates to function at the level of the biochemical reaction. We will address how the partitioning of multiple reactions at multiple scales result in complexity at the level of the organelle, and the cell. In the other, we will work downwards, addressing biological diversity in living organisms, the physiology of various systems essential for life, and how organisms interact with their environment to form ecosystems. Finally, we will bring together both strands of learning, showing how multiple interactions at multiple scales result in the complexity seen in the natural biological world

Chemistry Content Summary

We shall begin by discussing the origin of atomic orbitals, their shape, the associated quantum numbers and the rules governing the filling of orbitals with electrons, before seeing how this knowledge explains chemical properties and reactivity. We shall then see how the linear combination of atomic orbitals (LCAO) is used to construct molecular orbitals and so to explain the bonding and associated properties, including aspects of their bond vibration as evidenced by infrared spectroscopy, of some simple molecules. The course then turns to consider reacting mixtures of chemical substances, showing how thermodynamics governs the position of reaction equilibrium and outlining the theories of reaction kinetics used to interpret measurements of chemical reaction rate in terms of a rate law and a reaction mechanism. The underlying mathematics is considered in some detail and the overlap with physics (e.g. the Maxwell-Boltzmann distribution for speeds of gas molecules) and biology (e.g. enzyme kinetics) is highlighted. With these enabling concepts in place, we shall then turn to structure and reactivity of organic molecules, pertinent in particular to the chemistry and biology of living systems. Prefaced by a discussion of orbital hybridisation and bonding in carbon, and including the analytical elements of mass spectrometry and of nuclear-magnetic resonance (NMR) and infrared spectroscopies, we shall explain how organic molecules are named and represented, how different functional groups impart different reactivity and how the main reaction types (addition, substitution and elimination) occur in mechanistic terms. This is the central synthetic framework for everything from the elucidation of biosynthetic pathways in nature, to designing new molecules and materials for use in all branches of science.

Physics Content Summary

We will teach you how to make quantitative predictions about the physical world by combining physical principles to build mathematical models. You will be introduced to fundamental physical principles and some standard models of physics, including models for atoms, solids, liquids and gases, and light and sound. You will be guided in how to apply the principles of physics in new situations and manipulate mathematical formulae to build quantitative physical models. Your problem-solving strategies and strategies for identifying and remedying missing knowledge will be developed.

The number and complexity of the original assessments means that it is not practical to re-assess this module with identical re-assessments.

If you have failed the module overall (ie a final overall module mark of less than 40%) you will be required to sit a further single examination paper covering Biology, Chemistry and Physics. This mark will constitute the final mark for the module and be capped at 40%.

If you have been deferred for any of the written examinations, you will be expected to complete a deferred examination.

If you have been deferred for a single assessment other than a written examination, you will not normally be expected to submit a deferred assessment. Your mark will be based on other assessments.

If you have been deferred for two or more assessments, other than a written examination, per subject area (i.e. Biology, Chemistry, Physics), you will be required to undertake an additional MCQ test (Biology) or problem sheet (Chemistry, Physics).

The mark given for a re-assessment taken as a result of deferral will not be capped and will be treated as it would be if it were your first attempt at the assessment.

Basic reading:

Biology - Campbell and Reese, Biology (9th edition), Pearson International Edition, ISBN-13: 978-0321739759

Organic Chemistry - Clayden, Greeves and Warren, Organic Chemistry (2nd edition), ISBN-10: 0199270295, ISBN-13: 978-0199270293

Inorganic Chemistry - Housecroft and Sharpe, Inorganic Chemistry (4th Edition), ISBN-10: 0273742752, ISBN-13: 978-0273742753

Physical Chemistry - Atkins, Peter W.; de Paula, Julio (2010). Physical Chemistry (9th ed.). Oxford University Press. ISBN 978-0-19-954337-3

Physics - Young and Freedman, University Physics (with Modern Physics) (13^th edition), Addison-Wesley, ISBN 0-321-76219-3 (UL: 530 YOU)

ELE:  http://vle.exeter.ac.uk/course/view.php?id=3804

Web based and Electronic Resources:

Other Resources:

Reading list for this module: